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Serum or Plasma Electrophoresis Profile (Qualitative)

Published: August 9, 2026Updated: August 16, 2026

This test measures the distribution and relative amounts of different protein types in your blood, often used to detect abnormalities like infections, inflammation, or certain blood disorders.

Quick summary

["Electrophoresis helps identify protein patterns that may signal underlying health concerns."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
111977-5
Short code
Dx chrctr Blry tr Endscpy
Synonyms
Dx chrctr Blry tr Endscpy
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
endoscopy
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

Electrophoresis separates blood proteins based on their electrical charge and size. The test identifies bands corresponding to albumin, alpha-globulins, beta-globulins, and gamma-globulins, which can reflect conditions like multiple myeloma, autoimmune diseases, or nutritional deficiencies.

Why It’s Ordered

Your healthcare provider may order this test to investigate symptoms such as unexplained fatigue, swelling, or signs of chronic inflammation. It’s also used in monitoring conditions like multiple myeloma or hereditary disorders affecting protein levels.

Sample Preparation

A blood sample is drawn, typically from a vein in your arm. The serum or plasma is then separated and analyzed in a laboratory using an electric field to separate proteins by charge.

Common Uses and Interpretation

Abnormal patterns may indicate conditions like monoclonal gammopathy (excess of a single protein), liver disease, or infections. Results are compared to standard patterns to identify deviations.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical significance: This test is critical for diagnosing and managing conditions affecting protein balance. For example, elevated gamma-globulins may suggest immune disorders, while unusual band patterns could point to genetic or metabolic issues requiring further testing or treatment.

Short name

None

Frequently asked questions

How long will it take to get my results?
Results are usually available within 1 to 3 business days, depending on lab processing times. Follow-up with your healthcare provider is needed to discuss findings and next steps.
Can I eat or drink before this test?
No special preparation is needed for this test. However, avoid alcohol for 24 hours before drawing blood if your provider recommends it, as it may affect protein levels.
Is this test painful?
The blood draw itself may cause mild discomfort, but the procedure is quick and typically not considered painful. Most people experience only a brief pinch during the draw.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy