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C-reactive protein (CRP) concentration in serum/plasma

Published: August 9, 2026Updated: August 16, 2026

This test measures the level of C-reactive protein, a protein produced by the liver in response to inflammation in your body.

Quick summary

["CRP helps identify inflammation, often used to monitor conditions like infections, autoimmune diseases, or after surgery."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
112054-2
Short code
Dx chrctr Mnr ppl Endscpy
Synonyms
Dx chrctr Mnr ppl Endscpy
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
endoscopy
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why CRP Matters in Your Health

CRP is a marker that rises when your body fights inflammation. High levels may signal infections, injuries, or certain health conditions that require attention. Your doctor may order this test to check for inflammation, guide treatment, or monitor chronic conditions like arthritis or heart disease.

When This Test Is Done

Your doctor might recommend this test if you have symptoms of inflammation (like fever, pain, or swelling), if you’re recovering from surgery or illness, or if you have a known condition that causes chronic inflammation. It’s also sometimes used as a screening tool for heart disease or to track how well certain treatments are working.

What to Expect Before the Test

No special preparation is usually needed, but you may be asked to fast for 8–12 hours before the test if it’s part of a broader blood panel. On the day of the test, avoid strenuous activity or taking anti-inflammatory medications (like ibuprofen) unless your doctor approves.

What the Results Mean

Results are reported in milligrams per deciliter (mg/dL). A higher than normal CRP level may indicate inflammation, but it doesn’t always pinpoint the exact cause. Your doctor will interpret results in the context of your symptoms and medical history.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

CRP (Serum/Plasma)

Frequently asked questions

What causes elevated CRP levels?
Elevated CRP can result from infections (like pneumonia or urinary tract infections), injuries, surgeries, autoimmune diseases (like lupus or rheumatoid arthritis), or certain cancers. It can also be influenced by factors like age, obesity, or smoking. Low CRP levels may suggest your body is not actively inflamed.
Can CRP levels change over time?
Yes, CRP levels can fluctuate based on your health status. For example, they may spike after an infection or injury and then return to normal as your body heals. Your doctor may retest CRP levels to track changes, especially if you’re undergoing treatment for a chronic condition.
Is CRP the same as other inflammation markers?
No, CRP is one of many inflammation markers. Others, like erythrocyte sedimentation rate (ESR) or interleukin-6 (IL-6), serve different purposes and may be used alongside CRP for a more complete picture of inflammation.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy