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Serum or plasma concentration of dehydroepiandrosterone sulfate (DHEAS)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of a hormone called dehydroepiandrosterone sulfate (DHEAS) in your blood. DHEAS is a precursor to other sex hormones and plays a role in both male and female hormone regulation.

Quick summary

["DHEAS helps assess hormone balance and may be checked for conditions affecting sex hormones."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
112030-2
Short code
Dx PD Endscpy
Synonyms
Dx PD Endscpy
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
endoscopy
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Is DHEAS Used For?

DHEAS levels can help doctors evaluate hormone production, especially in conditions like adrenal gland disorders, early signs of aging-related hormone changes, or certain cancers. It may also be used in fertility evaluations or to monitor hormone therapy.

Why Might You Need This Test?

Your healthcare provider may order a DHEAS test if you have symptoms like low libido, irregular periods, fatigue, or signs of adrenal issues. It’s sometimes checked alongside other hormone tests, such as testosterone or cortisol.

How Is the Test Performed?

A blood sample is taken from a vein in your arm. The blood is then sent to a lab for analysis. The test typically takes a few days to return results, depending on lab processing times.

What Do Results Mean?

Results are compared to general reference ranges, but individual values can vary based on age, sex, and health status. High or low levels may signal underlying conditions that need further evaluation.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

DHEAS Level

Frequently asked questions

What causes abnormal DHEAS levels?
Abnormal DHEAS levels can result from adrenal gland disorders (e.g., Cushing’s syndrome or adrenal insufficiency), early signs of aging-related hormone changes, or conditions affecting hormone metabolism. It may also be influenced by medications or genetic factors.
How often should I get this test?
Your doctor will determine the frequency based on your symptoms, medical history, and specific needs. Routine screening for DHEAS is not typically recommended unless there’s a clinical reason to check it.
Can lifestyle changes affect DHEAS levels?
Yes, diet, stress levels, and certain medications can influence hormone levels, including DHEAS. Maintaining a balanced diet, managing stress, and avoiding excessive alcohol may support stable hormone function.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy