Endogenous steroid hormone profile (serum/plasma)

What This Test Measures

The test typically includes measurements for key steroid hormones such as cortisol (a stress hormone), aldosterone (regulates blood pressure), and sex hormones like testosterone (in men) or estrogen (in women). Some tests may also include dehydroepiandrosterone (DHEA), progesterone, or other adrenal or gonadal hormones depending on clinical needs.

Why It Matters in Your Health

Hormonal imbalances can lead to symptoms like fatigue, weight changes, irregular periods, high blood pressure, or difficulty managing stress. This test helps doctors diagnose conditions like Cushing’s disease, adrenal insufficiency, or hormonal disorders that require treatment.

Common Conditions Evaluated

This test is often used to diagnose or monitor conditions such as adrenal gland disorders (e.g., Addison’s disease or Cushing’s syndrome), thyroid dysfunction, or reproductive hormone imbalances (e.g., polycystic ovary syndrome or hypogonadism). It may also be part of a broader evaluation for metabolic or stress-related health concerns.

Sample Collection and Preparation

A blood sample is drawn from a vein in your arm. The blood is collected in a special tube that separates serum (liquid part) or plasma (blood without clotting factors) for testing. You may be asked to fast for 8–12 hours before the test if cortisol or other hormones are affected by food.