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Red blood cell (RBC) morphology with automated microcytometry (qualitative assessment of RBC size distribution)

Published: August 9, 2026Updated: August 17, 2026

This test evaluates the range of red blood cell sizes in your blood, which can help identify whether some cells are unusually small or large.

Quick summary

["Assessing RBC size variability may help diagnose conditions affecting blood cell production or function."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
33666-9
Short code
Dysmorphic RBC # Ur Micro
Synonyms
Dysmorphic RBC # Ur Micro
Category
chemistry
Sample
urine
Container
Sterile urine container
Units
N/A
Ref low
4.2
Ref high
5.9
Critical range
2 N/A – 7 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
microscopy-light
CPT
85041
SNOMED
900000000000003001
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may order this test if you have symptoms like fatigue, pale skin, or unusual bruising, or if tests show low red blood cell counts. It can also be part of routine screening for certain blood disorders.

What to Expect Before the Test

No special preparation is needed. A simple blood draw from a vein in your arm is all that’s required. The test measures RBC size using advanced technology that analyzes thousands of cells at once.

How the Results Are Interpreted

Results typically show whether most RBCs fall within a normal size range or if there’s a shift toward smaller (microcytic) or larger (macrocytic) cells. Abnormal patterns may signal conditions like iron deficiency, anemia, or genetic disorders.

Common Conditions Linked to Abnormal RBC Sizes

Microcytosis (small RBCs) may indicate iron deficiency, thalassemia, or chronic diseases. Macrocytosis (large RBCs) can suggest vitamin deficiencies (like B12 or folate), liver disease, or alcohol use.

Reference range

Adult males: 4.2-5.9; Females: 3.8-5.1 x 10^12/LN/A

Specimen: urine

No special preparation required. Stay well hydrated.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: Abnormal RBC size patterns often point to underlying health issues that require further investigation, such as blood disorders, nutritional deficiencies, or chronic illnesses. Early detection can guide treatment decisions.

Short name

RBC Size Distribution Check

Frequently asked questions

What causes RBC size variability to be checked?
Your doctor may recommend this test if you have symptoms like fatigue, pale skin, or unusual bruising, or if blood tests show low hemoglobin or red blood cell counts. It can also be part of diagnosing conditions like anemia or genetic blood disorders.
How long does it take to get results from this test?
Results are usually available within 24 to 48 hours, depending on your lab’s processing schedule. Your healthcare provider will discuss the findings with you during your follow-up visit.
Can lifestyle changes affect RBC size measurements?
Yes, certain lifestyle factors like diet (especially iron, vitamin B12, or folate), alcohol use, or chronic illnesses can influence RBC size. If you suspect lifestyle-related changes, discuss them with your provider before or after the test.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy