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Red Blood Cell Morphology with Differential Count (Comprehensive)

Published: August 9, 2026Updated: August 17, 2026

This test examines the shape, size, and appearance of your red blood cells (RBCs) and counts different types of white blood cells (WBCs) to help identify potential blood disorders.

Quick summary

["Assessing your RBCs and WBCs can help detect conditions like anemia, infections, or blood abnormalities."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
99864-1
Short code
Dysmorphic RBC # UrnS Comp Assist
Synonyms
Dysmorphic RBC # UrnS Comp Assist
Category
chemistry
Sample
urine
Container
Sterile urine container
Units
N/A
Ref low
4.2
Ref high
5.9
Critical range
2 N/A – 7 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
computer-assisted
CPT
85041
SNOMED
900000000000003001
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why This Test Is Done

Doctors may order this test to diagnose or monitor conditions such as anemia (low RBCs), infections, blood disorders (like leukemia or sickle cell disease), or other blood-related issues. It can also help evaluate symptoms like fatigue, pale skin, or unusual bruising.

What to Expect Before the Test

No special preparation is needed. You may have a small needle inserted into your arm or hand to draw a small amount of blood. If you’re concerned about pain or discomfort, let your healthcare provider know.

What the Test Results Mean

Results include measurements of RBC shape (e.g., normocytic, microcytic, macrocytic), WBC counts (neutrophils, lymphocytes, etc.), and sometimes red cell indices. Abnormal findings may signal infections, genetic disorders, or other health concerns.

Common Conditions Detected

This test can help identify conditions like iron deficiency anemia (small, pale RBCs), pernicious anemia (large RBCs), or infections (elevated WBCs). It may also reveal signs of bone marrow disorders or blood clotting issues.

Reference range

Adult males: 4.2-5.9; Females: 3.8-5.1 x 10^12/LN/A

Specimen: urine

No special preparation required. Stay well hydrated.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Abnormal RBC morphology or WBC counts can indicate underlying health problems that require further medical evaluation. For example, irregular RBC shapes may point to hereditary conditions, while elevated or low WBC counts can signal infections or immune system disorders.

Short name

RBC Morphology & Diff

Frequently asked questions

What does an abnormal RBC morphology or differential count mean?
An abnormal result may suggest conditions like anemia (e.g., microcytic RBCs for iron deficiency), infections (elevated neutrophils), or blood disorders (e.g., abnormal WBCs). Your doctor will discuss findings with you and may recommend additional tests.
How often should I get this test?
Frequency depends on your health. Some people get it annually for routine checkups, while others may need it more often if they have a condition like anemia or a history of blood disorders.
Can I eat or drink before this test?
No special diet or fasting is required. However, inform your doctor about any medications or supplements you’re taking, as they may affect results.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy