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Red Blood Cell Morphology with Qualitative Evaluation of Anisocytosis and Poikilocytosis (Urinalysis)

Published: August 9, 2026Updated: August 17, 2026

This test examines red blood cells (RBCs) in your urine to check for abnormal shapes and sizes, which may indicate underlying health conditions.

Quick summary

["Abnormal RBC shapes in urine can signal kidney issues or other systemic problems."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
58444-1
Short code
Dysmorphic RBC UrnS Ql Micro
Synonyms
Dysmorphic RBC UrnS Ql Micro
Category
chemistry
Sample
urine
Container
Sterile urine container
Units
N/A
Ref low
4.2
Ref high
5.9
Critical range
2 N/A – 7 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
microscopy-light
CPT
85041
SNOMED
900000000000003001
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What This Test Measures

The test evaluates red blood cells (RBCs) for two key abnormalities: **anisocytosis** (variation in RBC size) and **poikilocytosis** (variation in RBC shape). These changes can appear in urine due to kidney damage, bleeding disorders, or other conditions affecting RBC production or function.

Why It’s Done

Your healthcare provider may order this test if you have symptoms like blood in urine, frequent urination, or signs of kidney problems. It helps assess whether RBC abnormalities are linked to urinary tract issues or systemic diseases.

Possible Causes

Abnormal RBCs in urine can result from conditions such as kidney disease, urinary tract infections, hemolytic anemia, or certain medications. The presence of these cells may also indicate bleeding in the urinary tract.

What to Expect

No special preparation is needed. You’ll provide a urine sample, which is then analyzed under a microscope to detect RBC morphology. Results are qualitative (descriptive rather than numerical).

Reference range

Adult males: 4.2-5.9; Females: 3.8-5.1 x 10^12/LN/A

Specimen: urine

No special preparation required. Stay well hydrated.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Detecting abnormal RBCs in urine can signal kidney dysfunction, urinary tract bleeding, or systemic disorders like hemolytic anemia. Early identification may prompt further testing (e.g., blood work, imaging) to diagnose underlying causes and guide treatment.

Frequently asked questions

What does a positive result mean?
A positive result means your urine contains RBCs with unusual shapes or sizes. This could indicate kidney problems, urinary tract bleeding, or other conditions affecting RBC health. Your provider will discuss next steps based on your symptoms and lab findings.
Can diet affect this test?
Dietary factors like excessive salt, certain medications (e.g., NSAIDs), or dehydration may influence urine appearance but are less likely to directly alter RBC morphology in urine. Follow your provider’s advice for any specific dietary restrictions.
How long does it take to get results?
Results are typically available within 1–2 business days, depending on lab processing. Your healthcare provider will review them with you during your follow-up visit.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy