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Serum/plasma quantitative measurement of total protein concentration (mass concentration)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of protein in your blood, which helps your body stay healthy by transporting nutrients, fighting infections, and maintaining fluid balance.

Quick summary

["Total protein levels can signal health issues or help monitor conditions like kidney disease or malnutrition."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
105903-9
Short code
EAEC pAA plas aggR+aatA genes Stl Ql
Synonyms
EAEC pAA plas aggR+aatA genes Stl Ql
Category
chemistry
Sample
stool
Container
Clean container
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 g
Stability
Refrigerated: 24h, Frozen: 7d
TAT
4–24 hours
Order
routine

What Does Total Protein Tell Us About My Health?

Total protein includes both albumin and globulin proteins. Albumin helps maintain blood pressure and fluid balance, while globulins support immune function. Abnormal levels may indicate conditions like liver disease, kidney problems, or severe infections.

Why Might My Doctor Order This Test?

Your doctor may order a total protein test to check for kidney function, liver health, nutritional status, or signs of chronic diseases like multiple myeloma or cirrhosis.

How Is This Test Performed?

A blood sample is drawn from a vein, usually in your arm. The sample is then sent to a lab where it’s analyzed to measure protein concentration using standard laboratory techniques.

What Are Common Causes of Abnormal Results?

Low protein levels may result from malnutrition, liver disease, kidney failure, or excessive protein loss (e.g., from chronic diarrhea or kidney disease). High protein levels could indicate dehydration, multiple myeloma, or severe infections.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Elevated total protein can sometimes signal dehydration or conditions like multiple myeloma, where abnormal protein production occurs. Low levels often point to malnutrition, liver or kidney disease, or conditions causing excessive protein loss. Follow-up testing may be needed to determine the exact cause.

Short name

Total Protein

Frequently asked questions

How often should I get this test?
The frequency depends on your health status and any underlying conditions. Your doctor will determine how often to check this test based on your medical history and treatment plan.
What do my results mean if they’re outside the normal range?
If your results are outside the normal range, your doctor will discuss them with you and may recommend further tests or treatments to address the underlying cause.
Can diet affect my total protein test results?
Yes, diet can influence protein levels. High-protein diets or malnutrition may affect results, so it’s important to follow your doctor’s instructions about fasting or dietary restrictions before testing.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy