Skip to content

Serum/plasma substance concentration (qualitative) for general protein electrophoresis

Published: August 9, 2026Updated: August 16, 2026

This test measures the overall protein composition in your blood, often used to check for conditions affecting protein balance.

Quick summary

["Protein electrophoresis helps identify abnormal protein patterns that may signal underlying health issues."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
93400-0
Short code
E. aerog+amn+gergo DNA Bld Pos Ql NAA+pr
Synonyms
E. aerog+amn+gergo DNA Bld Pos Ql NAA+pr
Category
chemistry
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What This Test Measures

Protein electrophoresis separates blood proteins into different fractions (e.g., albumin, globulins) using an electric field. This helps detect imbalances that could indicate conditions like liver disease, kidney problems, or certain cancers.

Common Uses

Doctors may order this test to diagnose or monitor conditions such as multiple myeloma, lymphoma, or chronic liver disease. It can also help evaluate protein loss in urine or unexplained swelling.

How the Test Works

A small blood sample is drawn and mixed with a special solution. An electric current is applied to separate proteins by size and charge, creating distinct bands on a gel. The pattern is compared to normal ranges to identify abnormalities.

Preparation Tips

No special preparation is needed, but avoid heavy meals or excessive alcohol before the test. If you’re on certain medications, let your provider know to avoid potential interference.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Abnormal protein patterns may signal conditions like hypoalbuminemia (low albumin), monoclonal gammopathy (unusual protein spikes), or systemic diseases. Early detection can guide treatment decisions.

Frequently asked questions

Why might I need this test?
Your doctor may recommend this test if you have symptoms like unexplained weight loss, swelling, fatigue, or if they suspect a condition affecting protein production or metabolism.
What do the results mean?
Results show the relative amounts of different proteins. A doctor will interpret the pattern in relation to your symptoms and medical history. Mild abnormalities may require follow-up testing.
Can I eat or drink before the test?
Standard fasting is not required, but avoid heavy meals or alcohol 24 hours before testing to ensure accurate results.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy