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Serum/Plasma Substance Concentration by Immunoassay (General Protein Electrophoresis Profile)

Published: August 9, 2026Updated: August 16, 2026

This test measures the distribution of different proteins in your blood, often used to identify abnormalities in protein levels such as those seen in conditions like multiple myeloma, liver disease, or kidney problems.

Quick summary

["Helps diagnose and monitor conditions affecting protein balance in your blood."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
15473-2
Short code
EAV NAb Titr Ser Nt
Synonyms
EAV NAb Titr Ser Nt
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
neut
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

Electrophoresis separates blood proteins based on size and charge, allowing for the identification of distinct protein bands. This test typically includes measurements for albumin, globulins (including immunoglobulins), and other proteins. The results help assess overall protein distribution and identify potential imbalances.

Common Conditions Evaluated

Protein electrophoresis is commonly used to detect conditions such as multiple myeloma (a cancer of plasma cells), liver disease (affecting albumin production), kidney disease (leading to proteinuria), and certain autoimmune disorders. It may also be used to monitor treatment responses.

Sample Collection and Preparation

A blood sample is drawn from a vein, usually in the arm. The blood is then separated into serum or plasma for analysis. This test does not require fasting and is typically performed on fresh or refrigerated samples.

Interpreting Your Results

Results are presented as a graphical profile showing the relative amounts of different protein fractions. Abnormal patterns may indicate specific protein abnormalities, such as elevated or low levels of certain globulins or albumin. Your healthcare provider will interpret these results in the context of your medical history and symptoms.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Protein Electrophoresis Profile

Frequently asked questions

Why might my doctor order this test?
Your doctor may recommend this test if you have symptoms like unexplained weight loss, fatigue, frequent infections, swelling, or if they suspect conditions like multiple myeloma, liver disease, or kidney problems. It can also be used as part of routine monitoring for certain chronic conditions.
How long will I need to wait for results?
Results are usually available within a few days to a week, depending on lab processing times. Your healthcare provider will contact you with the results once they are ready.
Can I prepare for this test in any special way?
No special preparation is needed. You can eat and drink normally before the test, and you may be asked to avoid certain medications if they could interfere with the results, but this will be discussed with your healthcare provider.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy