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Epstein-Barr Virus Antibody Profile (IgG and IgM) - Serology

Published: August 9, 2026Updated: August 16, 2026

This test measures the presence of antibodies against Epstein-Barr virus (EBV) in your blood. Antibodies are proteins your immune system produces in response to infections.

Quick summary

["Helps diagnose or monitor Epstein-Barr virus infection or exposure."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
93711-0
Short code
EBV Ab Pnl Ser Donr
Synonyms
EBV Ab Pnl Ser Donr
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Does This Test Measure?

The test detects two types of antibodies: IgM and IgG. IgM antibodies appear early in an infection and typically decline over time. IgG antibodies develop later and can persist for years, indicating past or ongoing infection.

Why Might You Need This Test?

Doctors may order this test if you have symptoms like fever, fatigue, sore throat, or swollen lymph nodes that could suggest an EBV infection, such as mononucleosis. It may also be used to check if you’ve been exposed to EBV or to monitor chronic conditions linked to EBV.

When Are Results Used?

Results help determine if you have an active EBV infection, assess the severity of symptoms, or guide treatment decisions. IgM positivity often means recent infection, while IgG positivity suggests past exposure or chronic infection.

What to Expect Before the Test

No special preparation is needed. You’ll have a small needle inserted into your arm to draw blood. If you’re nervous, let your healthcare provider know—they can offer comfort measures.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

EBV Antibody Test

Frequently asked questions

How long will it take to get my results?
Results are typically available within 1–3 business days, depending on lab processing times. Your doctor will discuss them with you during your follow-up visit.
Can I have false-positive or false-negative results?
While rare, false results can occur due to cross-reactions with other viruses or lab errors. If your symptoms persist or results are unclear, your doctor may repeat the test or order additional tests.
Does this test show if I’m contagious?
Yes, IgM antibodies indicate an active infection and suggest you may be contagious, especially during the early stages. IgG alone does not indicate contagiousness but confirms past exposure.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy