Epstein-Barr Virus Antibody Titration (IgG and IgM)
This test measures the levels of Epstein-Barr virus (EBV) antibodies in your blood to help determine if you’ve been exposed to the virus and whether your immune response is active.
["Assesses past or current EBV infection and immune response timing."]
Key facts at a glance
- LOINC
- 49069-8
- Short code
- EBV Ab Titr Ser
- Synonyms
- EBV Ab Titr Ser
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What Does This Test Measure?
The test detects two types of antibodies: IgG, which typically appears after initial infection and remains for life, and IgM, which indicates a recent or acute infection. The antibody levels are reported as a titer, or concentration, to show how strongly your immune system is responding.
Why Might You Need This Test?
Healthcare providers may order this test if you have symptoms like fever, fatigue, sore throat, or swollen lymph nodes that could suggest EBV infection (e.g., mononucleosis). It’s also used to monitor chronic conditions like infectious mononucleosis or to assess immune function in certain cases.
What to Expect Before the Test
No special preparation is needed. You’ll have a small needle inserted into a vein (usually in your arm) to draw blood. The process takes about 5 minutes, and you may feel a brief pinch. If you’re nervous, let your healthcare provider know.
What to Expect During the Test
After drawing blood, a bandage will cover the site. You can resume normal activities immediately. If you experience bruising or discomfort, apply gentle pressure to the area.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
High IgM levels suggest an active EBV infection, while high IgG levels indicate past infection. A rising IgG titer over time can help track immune response or chronic infection. This test helps diagnose conditions like mononucleosis, assess immune function, or guide treatment decisions in rare cases.
Short name
EBV Antibody Profile
Frequently asked questions
How long does it take to get results?
What do my results mean?
Can I have this test if I’m pregnant?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy