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Vitamin D Binding Protein (DBP) Concentration (Serum/Plasma)

Published: August 9, 2026Updated: August 16, 2026

This test measures the level of vitamin D binding protein, a protein in your blood that helps transport vitamin D and other hormones.

Quick summary

["Understanding your vitamin D binding protein levels can help assess how well your body processes certain vitamins and hormones."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
49355-1
Short code
EBV DNA # Amn NAA+probe
Synonyms
EBV DNA # Amn NAA+probe
Category
chemistry
Sample
fluid
Container
Sterile tube
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
Specimen volume
2-5 mL
Stability
Room temperature: 2h, Refrigerated: 24h
Hemolysis max
300
TAT
4–24 hours
Order
routine

Why It’s Done

Your healthcare provider may order this test if you have symptoms related to vitamin D metabolism, such as bone pain, muscle weakness, or if you have conditions like kidney disease or certain hormonal disorders. It may also be part of a broader evaluation for vitamin D deficiency or excess.

What to Expect

A blood sample will be taken from a vein in your arm. You may feel a small pinch when the needle is inserted, but the process is quick. No special preparation is usually needed, though you may be asked to fast for a few hours if instructed.

Sample Collection and Testing

The blood sample is sent to a lab where it is analyzed using a specialized immunoassay method to measure the concentration of vitamin D binding protein.

Interpretation and Results

Results are typically reported as a concentration value. Your provider will compare these results to your health history and other test results to determine if they are within expected ranges or if further action is needed.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Vitamin D binding protein plays a role in transporting vitamin D and other fat-soluble hormones in your bloodstream. Abnormal levels may indicate underlying conditions affecting hormone metabolism, kidney function, or liver health. It can also be relevant in research or specialized diagnostic contexts.

Short name

DBP

Frequently asked questions

What does a high or low vitamin D binding protein level mean?
High levels may be associated with certain genetic conditions or liver/kidney disorders, but they can also occur naturally. Low levels might suggest kidney disease or other metabolic issues, though they are less commonly the primary focus in clinical practice.
How often should I get this test?
This test is not routinely recommended for general health screening. Your provider will determine if and how often it is needed based on your medical history, symptoms, or other test results.
Can diet or supplements affect vitamin D binding protein levels?
While vitamin D binding protein itself is not directly influenced by diet or supplements, conditions like kidney disease or liver dysfunction may be. Your provider may recommend lifestyle changes or other tests if abnormalities are found.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy