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Epstein-Barr Virus DNA (Serum/Plasma) Quantitative

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of Epstein-Barr virus (EBV) DNA in your blood. EBV is a common virus that can cause infections like mononucleosis and may be linked to certain cancers.

Quick summary

["Checking EBV DNA helps doctors monitor infection progression or guide treatment for conditions like infectious mononucleosis or lymphoma."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
108595-0
Short code
EBV DNA Msmt Tiss
Synonyms
EBV DNA Msmt Tiss
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Is Epstein-Barr Virus (EBV)?

Epstein-Barr virus (EBV) is a type of herpesvirus that can cause infections in the throat, lymph nodes, and other parts of the body. It’s often spread through saliva and can lead to illnesses like mononucleosis, but it can also remain dormant in the body for years.

Why Is This Test Done?

Your doctor may order this test if you have symptoms of EBV infection (e.g., fever, swollen lymph nodes, fatigue) or if you’re being evaluated for conditions like infectious mononucleosis, chronic fatigue syndrome, or certain cancers linked to EBV.

How Is the Test Performed?

A blood sample is taken from a vein in your arm. The sample is then analyzed in a lab to detect and measure EBV DNA using advanced techniques like polymerase chain reaction (PCR).

What Do Results Mean?

Results show the amount of EBV DNA in your blood. Higher levels may indicate an active infection, while lower or undetectable levels suggest the virus is less active. Your doctor will interpret results in the context of your symptoms and medical history.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

EBV DNA Level

Frequently asked questions

How often should I expect this test?
This test is typically done once or twice during an evaluation, depending on your symptoms and medical needs. Follow-up tests may be needed if your doctor suspects ongoing infection or disease progression.
Can EBV DNA levels change over time?
Yes, EBV DNA levels can fluctuate. During an active infection, they may rise and fall as the virus replicates. After treatment or recovery, levels often decrease or become undetectable.
Is there anything I can do to lower EBV DNA levels?
While there’s no direct way to lower EBV DNA levels, managing symptoms (e.g., rest, hydration) and following prescribed treatments (like antiviral medications) can help control infection. Avoid close contact with others if you have symptoms to prevent spreading the virus.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy