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Serum or plasma concentration of vitamin E (alpha-tocopherol)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of vitamin E, a fat-soluble antioxidant, in your blood. Vitamin E helps protect cells from damage caused by free radicals.

Quick summary

["Vitamin E supports cell health and immune function; low levels may indicate nutritional deficiencies or absorption issues."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
16823-7
Short code
EBV EA Ab Ser IA-aCnc
Synonyms
EBV EA Ab Ser IA-aCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ia
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms like muscle weakness, nerve problems, or frequent infections. It could also be used to monitor vitamin E levels in conditions like cystic fibrosis or certain genetic disorders affecting fat absorption.

What to Expect Before the Test

No special preparation is usually needed, but you may be asked to fast for 8–12 hours before the draw if your test involves a fasting sample. Wear a loose shirt for easy access to your vein.

How the Test Works

A blood sample is taken from a vein in your arm. The blood is processed to separate serum or plasma, where vitamin E levels are measured using a specialized lab technique (likely immunoassay or similar).

What the Results Mean

Results are compared to a general reference range for healthy adults. Very low levels may suggest poor vitamin E intake, malabsorption, or certain medical conditions. High levels could indicate over-supplementation or liver disease.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Vitamin E Level

Frequently asked questions

What causes low vitamin E levels?
Low vitamin E levels can result from poor diet (e.g., very low-fat diet), malabsorption disorders (like celiac disease or Crohn’s), bile duct blockages, or certain medications that interfere with fat absorption.
What symptoms might I experience if my vitamin E level is low?
Symptoms of deficiency may include muscle weakness, balance problems, vision changes, or frequent infections. Some people experience no symptoms until deficiency is severe.
How is vitamin E typically treated?
Treatment often involves dietary changes (e.g., more nuts, seeds, or fortified foods) or vitamin E supplements, depending on the underlying cause. Your doctor may adjust your supplement dose based on test results.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy