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Serum or plasma concentration of vitamin E (alpha-tocopherol)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of vitamin E, a fat-soluble antioxidant found in foods like nuts, seeds, and leafy greens. It helps protect cells from damage caused by free radicals.

Quick summary

["Vitamin E supports heart health, immune function, and skin protection."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
7882-4
Short code
EBV EA Ab Ser Ql
Synonyms
EBV EA Ab Ser Ql
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order this test if you have symptoms of vitamin E deficiency, such as nerve problems, muscle weakness, or vision issues. It may also be checked in people with certain genetic disorders, malabsorption conditions (like celiac disease), or long-term fat malabsorption. Additionally, it could be part of a broader nutritional assessment or monitoring for conditions affecting fat-soluble vitamins.

What Does a Low or High Level Mean?

Low levels of vitamin E might suggest poor absorption, certain genetic disorders, or long-term dietary deficiencies. High levels could indicate liver disease, certain medications, or excessive vitamin E intake from supplements.

How Is the Test Performed?

A blood sample is taken from a vein in your arm. The sample is sent to a lab where it is analyzed to measure the concentration of vitamin E. The test typically requires fasting, but this may vary by lab protocol.

What Should You Expect Before the Test?

No special preparation is usually needed, but you may be asked to avoid certain medications (like some blood thinners) or foods that could interfere with results. Always follow your healthcare provider’s instructions.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Vitamin E plays a critical role in preventing oxidative stress, which can damage cells and contribute to chronic diseases like heart disease or neurodegenerative conditions. Deficiency is rare but can lead to serious health issues, while very high levels may pose risks depending on the cause.

Short name

Vitamin E Level

Frequently asked questions

What are the normal results?
Normal results vary by lab and method, but a deficiency is often identified if levels are significantly below expected ranges. Your healthcare provider will interpret results in the context of your overall health and symptoms.
Can vitamin E levels change with diet?
Yes, dietary intake of vitamin E from foods like vegetable oils, nuts, and seeds can affect test results. Supplements may also impact levels, so it’s important to discuss any recent changes with your provider.
Does this test require fasting?
Most labs do not require fasting, but always confirm with your healthcare provider or lab instructions, as some may have specific guidelines.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy