Serum or plasma concentration of vitamin E (alpha-tocopherol)

Why Is This Test Done?

Your healthcare provider may order this test to check for vitamin E deficiency, especially if you have symptoms like muscle weakness, nerve problems, or a history of certain medical conditions that affect fat absorption (e.g., liver disease, malabsorption syndromes). It can also be part of routine screening or monitoring for conditions like cystic fibrosis or premature infants.

What to Expect Before the Test

No special preparation is usually needed. You may be asked to fast for 8–12 hours before the test if blood is drawn from a vein. If a urine or other specimen is used, follow any specific instructions your provider gives you.

How the Test Is Performed

Blood is drawn from a vein in your arm, or a sample of urine or other body fluid may be collected. The sample is then sent to a lab for analysis using methods like immunoassay or enzymatic techniques to measure vitamin E levels.

Possible Results and Their Meaning

Results are compared to a reference range, which varies by lab. Low levels may indicate deficiency, while high levels could suggest certain medications, liver disease, or other conditions. Your provider will interpret results in the context of your health.