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Serum or plasma concentration of vitamin E (alpha-tocopherol)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of vitamin E, a fat-soluble antioxidant, in your blood. Vitamin E helps protect cells from damage caused by free radicals.

Quick summary

["Vitamin E supports immune function and may help reduce oxidative stress in the body."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
42497-8
Short code
EBV EA Ab Titr CSF
Synonyms
EBV EA Ab Titr CSF
Category
chemistry
Sample
csf
Container
Sterile tube
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
1-2 mL
Stability
Immediate analysis required, Refrigerated: 1h
Hemolysis max
200
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order this test to check for vitamin E deficiency, especially if you have symptoms like muscle weakness, nerve problems, or frequent infections. It can also be part of a broader evaluation for conditions affecting fat absorption or liver function.

What to Expect Before the Test

No special preparation is usually needed, but you may be asked to fast for 8–12 hours before the test if it involves drawing blood from a vein. If you’re taking vitamin E supplements, let your provider know.

How the Test Is Performed

A healthcare professional will collect a blood sample from a vein in your arm using a needle. The blood is then sent to a lab for analysis to measure vitamin E levels.

Possible Results and Interpretation

Results are compared to standard reference ranges for vitamin E. Low levels may indicate deficiencies or underlying health conditions affecting absorption or metabolism.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Vitamin E Level

Frequently asked questions

What causes vitamin E levels to be low?
Low vitamin E levels can result from conditions that impair fat absorption (like cystic fibrosis or short bowel syndrome), liver disease, certain genetic disorders, or long-term use of certain medications. Lifestyle factors, such as poor diet or excessive alcohol consumption, may also contribute.
What symptoms might indicate a vitamin E deficiency?
Symptoms may include muscle weakness, coordination problems, nerve damage (e.g., tingling or numbness), frequent infections, or vision issues. However, many people with mild deficiencies may not experience symptoms until the deficiency is more severe.
Can vitamin E supplements affect this test?
Yes, taking high-dose vitamin E supplements may temporarily raise your blood levels. If you’re on supplements, inform your provider before the test to avoid misleading results.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy