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Serum or Plasma Albumin to Globulin Ratio (A/G Ratio)

Published: August 9, 2026Updated: August 16, 2026

This test measures the ratio of albumin and globulin proteins in your blood, which helps assess protein balance and potential liver or kidney issues.

Quick summary

["The A/G ratio can reveal protein disorders or organ function problems."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
94102-1
Short code
EBV EA-D IgA SerPl IA-aCnc
Synonyms
EBV EA-D IgA SerPl IA-aCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ia
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Is Albumin and Globulin?

Albumin is a protein made by your liver that helps maintain fluid balance in your body. Globulins are another group of proteins that include antibodies and transport proteins. Together, they support immunity, blood clotting, and nutrient transport.

Why Is the A/G Ratio Important?

A higher albumin level (lower A/G ratio) often suggests healthy protein levels, while a lower albumin and higher globulin (higher A/G ratio) may indicate conditions like chronic liver disease, kidney problems, or inflammation.

How Is This Test Done?

A blood sample is drawn from a vein, typically in your arm. The lab analyzes the serum or plasma to measure albumin and globulin levels separately, then calculates their ratio.

What Might Affect Results?

Factors like diet, medications (e.g., steroids), liver or kidney disease, infections, or recent blood loss can influence albumin and globulin levels, thus affecting the A/G ratio.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: The A/G Ratio Can Signal Underlying Conditions

Short name

A/G Ratio

Frequently asked questions

How often will I need this test?
This test is often ordered as part of a general health checkup, to monitor chronic conditions like liver disease or kidney problems, or to investigate symptoms such as swelling, fatigue, or unexplained weight loss. Your healthcare provider will determine how frequently you need it based on your health status and needs.
What are the normal ranges for this test?
There are no strict numeric reference ranges provided here since they can vary by lab. Instead, your results will be compared to your individual baseline or clinical context. Your doctor will interpret the results in relation to your overall health and symptoms.
Can I prepare for this test?
No special preparation is needed for this blood test. However, avoid heavy meals before the draw, and inform your provider about any medications you’re taking, as they may affect results.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy