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Serum or plasma concentration of vitamin E (alpha-tocopherol)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of vitamin E, a fat-soluble antioxidant found in your blood. Vitamin E helps protect cells from damage caused by free radicals.

Quick summary

["Vitamin E supports cell health and immune function; low levels may indicate nutritional deficiencies or absorption issues."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
23972-3
Short code
EBV EA IgG Titr CSF
Synonyms
EBV EA IgG Titr CSF
Category
chemistry
Sample
csf
Container
Sterile tube
Units
N/A
Ref low
8
Ref high
61
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82977
SNOMED
3110003
Specimen volume
1-2 mL
Stability
Immediate analysis required, Refrigerated: 1h
Hemolysis max
200
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms like muscle weakness, nerve problems, or skin issues that could be linked to low vitamin E levels. It may also be used to monitor conditions affecting fat absorption, such as certain gastrointestinal disorders or liver disease.

What to Expect Before the Test

No special preparation is usually needed, but you may be asked to fast for 8–12 hours before the draw if the sample is taken from serum. Avoid taking vitamin E supplements for 24 hours before testing to ensure accurate results.

During the Test

A small needle will be inserted into your arm to draw blood. You may feel a brief pinch, but the process is quick. The blood is then sent to a lab for analysis.

What the Results Mean

Results are compared to a reference range specific to your lab. Low levels may signal vitamin E deficiency, while high levels could indicate overconsumption or certain metabolic conditions. Your provider will discuss findings with you.

Reference range

Adult males: 8-61 U/L; Adult females: 5-36 U/LN/A

Specimen: csf

No special preparation required. Avoid fatty meals before the test if possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Vitamin E Level

Frequently asked questions

Low vitamin E levels may be associated with conditions like cystic fibrosis, short bowel syndrome, or certain genetic disorders affecting fat metabolism. It can also be a marker for malnutrition or malabsorption issues.
This test helps diagnose or monitor deficiencies that could impact nerve function, immune response, or skin health. High levels may require further investigation to rule out over-supplementation or rare metabolic disorders.
How long will I need to wait for results?
Results typically arrive within 1–3 business days, depending on your lab’s processing time. Your healthcare provider will contact you once they’re ready to discuss them.
Can I eat or drink before this test?
For serum tests, fasting for 8–12 hours is often recommended. If your lab uses plasma, follow their instructions—some may allow water but no food. Always check with your provider or lab staff.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy