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Vitamin E (alpha-tocopherol) concentration in serum/plasma

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of vitamin E, a fat-soluble antioxidant, in your blood. Vitamin E helps protect cells from damage caused by free radicals.

Quick summary

["Vitamin E supports cell health and immune function; low levels may indicate nutritional deficiencies or health concerns."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
23971-5
Short code
EBV EA IgG Titr Ser
Synonyms
EBV EA IgG Titr Ser
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
8
Ref high
61
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82977
SNOMED
3110003
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order this test to check for vitamin E deficiency, especially if you have symptoms like muscle weakness, nerve problems, or a history of certain medical conditions. It can also be part of a broader evaluation for malabsorption issues or chronic illnesses like cystic fibrosis.

What to Expect Before the Test

No special preparation is usually needed. You may be asked to fast for 8–12 hours before the test if it involves drawing blood from a vein. If you’re taking vitamin E supplements, let your provider know, as they may affect results.

How the Test Is Performed

A blood sample is taken from a vein in your arm using a needle. You may feel a small pinch, but it usually doesn’t cause significant discomfort. The blood is then sent to a lab for analysis.

What the Results Mean

Results are compared to a reference range, but exact values can vary by lab. Low levels may suggest poor absorption, liver disease, or certain genetic conditions. High levels could indicate excessive supplementation or rare metabolic disorders.

Reference range

Adult males: 8-61 U/L; Adult females: 5-36 U/LN/A

Specimen: serum

No special preparation required. Avoid fatty meals before the test if possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Vitamin E Level

Frequently asked questions

What Are Common Causes of Low Vitamin E Levels?
Low vitamin E levels can result from conditions that impair fat absorption (e.g., celiac disease, Crohn’s disease), liver problems, or certain genetic disorders. It may also appear in people with chronic kidney disease or those who avoid healthy fats in their diet.
What Are Common Causes of High Vitamin E Levels?
Excessive vitamin E intake from supplements or certain medications can lead to elevated levels. Rarely, high levels may be linked to metabolic disorders or liver disease, but further testing would be needed to confirm.
How Often Should This Test Be Done?
This test is typically ordered as needed, often when symptoms or risk factors (like malabsorption) are present. If you have chronic conditions, your provider may recommend periodic monitoring based on your health status.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy