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Serum or plasma concentration of vitamin E (alpha-tocopherol)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of vitamin E, a fat-soluble antioxidant found in your blood. Vitamin E helps protect cells from damage caused by free radicals.

Quick summary

["Vitamin E supports cell health and immune function; low levels may indicate nutritional deficiencies or health concerns."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
23995-4
Short code
EBV EA IgG Titr Ser IF
Synonyms
EBV EA IgG Titr Ser IF
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
8
Ref high
61
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
if
CPT
82977
SNOMED
3110003
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order this test to check for vitamin E deficiency, especially if you have symptoms like muscle weakness, nerve problems, or a history of certain medical conditions that affect fat absorption. It can also be part of routine blood work or screening for genetic disorders.

What to Expect Before the Test

No special preparation is usually needed, but you may be asked to fast for 8–12 hours before the test if it involves drawing blood from a vein. If it’s a urine test, you might need to collect a sample over 24 hours. Always follow your provider’s instructions.

What Happens During the Test?

For blood tests, a healthcare professional will insert a needle into a vein (often in your arm) to draw a small amount of serum or plasma. For urine tests, you’ll collect a sample in a container over a specified period. The sample is then sent to a lab for analysis.

What Are Possible Results?

Results are reported as a concentration (e.g., milligrams per deciliter). Your provider will compare your result to standard reference ranges and discuss it with you based on your health history and symptoms.

Reference range

Adult males: 8-61 U/L; Adult females: 5-36 U/LN/A

Specimen: serum

No special preparation required. Avoid fatty meals before the test if possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Vitamin E Level

Frequently asked questions

What causes vitamin E deficiency?
Deficiency can result from poor diet (low intake of nuts, seeds, or fortified foods), conditions that impair fat absorption (like pancreatitis or cystic fibrosis), or medications that interfere with vitamin E metabolism.
What symptoms might I experience if my vitamin E level is low?
Symptoms may include muscle weakness, nerve damage (tingling/numbness), vision problems, or fatigue. Some people with severe deficiency may develop neurological issues, but symptoms vary widely.
Can vitamin E levels be affected by diet or supplements?
Yes, dietary intake (e.g., almonds, spinach) and supplements can influence results. If you take vitamin E supplements, inform your provider, as they may need to adjust your test interpretation.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy