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Epstein-Barr Virus Nuclear Antigen Antibody, IgG (Serum/Plasma)

Published: August 9, 2026Updated: August 16, 2026

This test measures the level of antibodies against Epstein-Barr virus (EBV) in your blood. Antibodies are proteins your immune system produces to help fight infections.

Quick summary

["This test helps track your immune response to EBV, an infection commonly associated with mononucleosis."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
22296-8
Short code
EBV NA Ab Ser Ql
Synonyms
EBV NA Ab Ser Ql
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms of EBV infection, such as fever, fatigue, swollen lymph nodes, or sore throat. It may also be used to diagnose or monitor conditions linked to EBV, like certain cancers or immune disorders, or to assess long-term immunity after infection.

What to Expect Before the Test

No special preparation is needed for this blood test. You may have a small needle inserted into your arm to draw blood, which usually takes a few minutes. If you’re on blood thinners or have a history of bleeding issues, let your provider know.

What the Test Results Mean

Positive results indicate you have developed antibodies to EBV, meaning you’ve likely been exposed to the virus at some point. High levels may suggest recent infection or an active immune response. Results alone don’t confirm a current infection; they show past exposure or immunity.

Common Uses and Limitations

This test is useful for diagnosing past EBV exposure but isn’t definitive for active infection. It can’t distinguish between different types of EBV-related conditions. Always discuss results with your provider for accurate interpretation.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

EBV IgG Antibody

Frequently asked questions

What does a positive result mean for my health?
A positive result means your body has produced antibodies to EBV, indicating past exposure. This doesn’t necessarily mean you’re currently infected, but it confirms your immune system has recognized the virus. If you’re concerned about symptoms or health risks, talk to your provider.
Can this test detect active EBV infection?
No, this test measures IgG antibodies, which develop after infection. For active EBV infection, your provider might order additional tests or look for symptoms like fever, fatigue, or swollen glands.
How long do I need to wait for results?
Results are typically available within 1–3 business days. Your provider will discuss them with you during your follow-up visit, so timing depends on your appointment schedule.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy