Epstein-Barr Virus Nuclear Antigen (EBNA) Antibody Titration by Immunoassay
This test measures your immune response to the Epstein-Barr virus (EBV), a common virus that can cause infections like mononucleosis. It helps determine if your body has developed antibodies against the virus’s nuclear antigen.
["Assesses long-term EBV exposure and immune response."]
Key facts at a glance
- LOINC
- 21260-5
- Short code
- EBV NA Ab Titr Ser IF
- Synonyms
- EBV NA Ab Titr Ser IF
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- if
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why This Test Matters
EBV is often called the 'infection that stays' because it can remain in your body for life. After an initial infection, your immune system may produce antibodies like EBNA, which can persist. This test specifically looks for EBNA antibodies to check if you’ve had a past EBV infection or if your immune system is still responding to it.
What the Test Measures
The EBNA antibody test detects the presence and level of EBNA antibodies in your blood. These antibodies are produced by your immune system in response to the virus’s nuclear proteins. The test helps differentiate between recent and past infections, though it doesn’t indicate active disease.
Preparation and Sample Collection
No special preparation is needed for this blood test. A healthcare provider will draw blood from a vein, usually in your arm. The sample is sent to a lab for analysis using an immunoassay method to measure antibody levels.
What to Expect After the Test
You may experience mild discomfort or bruising at the injection site, but this usually fades quickly. Results are typically ready within a few days to a week, depending on lab processing times. Your healthcare provider will discuss the results with you during a follow-up visit.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
EBNA Antibody Test
Frequently asked questions
How long does it take to get results from this test?
Can this test be used to diagnose active EBV infection?
Is there any risk or side effect associated with this blood test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy