Epstein-Barr Virus Nuclear Antigen IgG Antibody (Serum)
This test measures the presence of antibodies to the Epstein-Barr virus (EBV) in your blood, specifically those that target the nuclear antigen of the virus. These antibodies indicate past or current infection.
["This test helps determine if you’ve been exposed to EBV, which can cause infections like mononucleosis."]
Key facts at a glance
- LOINC
- 111357-0
- Short code
- EBV NA IgG Msmt Ser
- Synonyms
- EBV NA IgG Msmt Ser
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- CPT
- 82784
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What This Test Measures
The test detects IgG antibodies produced by your immune system in response to EBV infection. IgG antibodies are typically present after an initial infection has resolved, providing long-term immunity. This test is often used to confirm past exposure rather than active infection.
Why It Matters in Your Health
EBV is a common virus that can affect anyone. While most people recover fully, some infections may cause complications, especially in immunocompromised individuals. Measuring EBV IgG helps doctors assess exposure history, monitor chronic conditions like infectious mononucleosis, or evaluate risks in certain medical scenarios.
When You Might Need This Test
Your healthcare provider may recommend this test if you have symptoms of EBV infection (e.g., fatigue, sore throat, swollen lymph nodes), if you’re investigating unexplained immune system issues, or if you’re at higher risk for EBV-related diseases (e.g., due to weakened immunity). It can also be part of routine screening in certain clinical settings.
What to Expect Before the Test
No special preparation is needed. You’ll have a small needle inserted into your arm to draw blood. The process takes a few minutes, and you may feel slight discomfort. If you’re on blood thinners or have a history of bleeding issues, let your doctor know beforehand.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical Significance
Short name
EBV IgG Antibody
Frequently asked questions
How long does it take to get results?
Can this test detect an active EBV infection?
Is this test covered by insurance?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy