Epstein-Barr Virus (EBV) Nuclear Antigen IgG Antibody, Serum

Why This Test Is Done

Your healthcare provider may order this test if you have symptoms of EBV infection, such as fatigue, sore throat, or swollen lymph nodes. It can also be used to monitor chronic conditions like infectious mononucleosis or to assess immune function in certain situations.

What to Expect Before the Test

No special preparation is needed. You’ll provide a blood sample, usually drawn from your arm. The test involves a small needle, and you may feel a brief pinch. If you’re pregnant, have a bleeding disorder, or take blood-thinning medications, let your provider know before the test.

What the Test Results Mean

Positive results indicate you’ve been exposed to EBV and developed IgG antibodies, which typically remain in your system for life. Negative results suggest no current EBV exposure or insufficient antibody presence. Results alone don’t diagnose EBV; they’re used alongside clinical findings.

Common Causes of Positive Results

Positive results are common in people who have recovered from EBV infection, such as those with mononucleosis. They may also appear in individuals with chronic EBV carriers or those with certain immune-related conditions.