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Epstein-Barr Virus (EBV) Nuclear Antigen IgG Antibody, Serum

Published: August 9, 2026Updated: August 16, 2026

This test measures the presence of antibodies to the Epstein-Barr virus (EBV) in your blood. It helps determine if you’ve been exposed to the virus and whether your immune system has mounted an immune response.

Quick summary

["This test helps track past or current EBV infection and immune response."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
23994-7
Short code
EBV NA IgG Titr CSF IF
Synonyms
EBV NA IgG Titr CSF IF
Category
chemistry
Sample
csf
Container
Sterile tube
Units
N/A
Ref low
8
Ref high
61
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
if
CPT
82977
SNOMED
3110003
Specimen volume
1-2 mL
Stability
Immediate analysis required, Refrigerated: 1h
Hemolysis max
200
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may order this test if you have symptoms like fatigue, sore throat, or swollen lymph nodes that could be linked to EBV infection. It may also be used to monitor chronic conditions like infectious mononucleosis or to assess immune function in certain situations.

What to Expect Before the Test

No special preparation is needed. You’ll have a small needle inserted into your arm to draw blood. It usually takes a few minutes, and you may feel a brief pinch. If you’re on blood thinners, let your provider know before the test.

What the Test Results Mean

Positive results indicate you’ve been exposed to EBV and likely have developed antibodies. The presence of these antibodies doesn’t necessarily mean you’re currently infected, but it shows your body has recognized the virus. Negative results suggest no detectable antibodies, meaning either you’ve never been exposed or the test was taken too early.

Common Reasons for Testing

EBV IgG tests are often used to diagnose or confirm past EBV infections, monitor chronic conditions like mononucleosis, or assess immune responses in certain medical scenarios.

Reference range

Adult males: 8-61 U/L; Adult females: 5-36 U/LN/A

Specimen: csf

No special preparation required. Avoid fatty meals before the test if possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

EBV IgG Antibody (Nuclear Antigen)

Frequently asked questions

How long will it take to get my results?
Results are typically available within 1 to 3 business days, depending on your lab. Follow-up with your healthcare provider to discuss the meaning of your results.
Can I have this test if I’m pregnant?
Yes, this test is generally safe during pregnancy. However, always discuss any tests with your healthcare provider to ensure it’s appropriate for your situation.
Does this test detect active EBV infection?
This test primarily detects past exposure to EBV through antibodies. It does not specifically measure active infection, which would require additional tests like viral load or viral capsid antigen testing.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy