Skip to content

Epstein-Barr Virus Nuclear Antigen IgG Antibody (Serum/Plasma)

Published: August 9, 2026Updated: August 16, 2026

This test measures the presence of antibodies to Epstein-Barr virus (EBV) in your blood, specifically targeting the nuclear antigen. These antibodies indicate past or current infection with EBV, a common virus that can affect the immune system.

Quick summary

["This test helps determine if you’ve been exposed to EBV, which can cause infections like mononucleosis or may be linked to certain long-term health conditions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
7884-0
Short code
EBV NA IgM Ser Ql
Synonyms
EBV NA IgM Ser Ql
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Does This Test Measure?

The test detects IgG antibodies against EBV’s nuclear antigen, which develop after initial infection. IgG antibodies typically remain in your blood for years, providing long-term immunity. This is a confirmatory test, often used after an initial screening for EBV exposure.

Why Might Your Doctor Order This Test?

Your doctor may recommend this test if you have symptoms of EBV infection (e.g., fatigue, sore throat, swollen lymph nodes), if you’ve been exposed to someone with EBV, or if you’re evaluating conditions linked to EBV, such as certain cancers or autoimmune diseases.

What to Expect During the Test

A small blood sample is drawn from a vein in your arm. The sample is then sent to a lab for analysis. Results are usually available within a few days. No special preparation is needed.

Common Reasons for Positive Results

A positive result means you likely had EBV at some point. This doesn’t necessarily mean you’re currently infected, but it confirms past exposure. Chronic infections or reactivation can also produce these antibodies.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

EBV IgG Antibody

Frequently asked questions

What does a positive result mean for my health?
A positive result indicates you’ve been exposed to EBV, which is very common. It doesn’t always mean you’re sick now, but it confirms your body has developed immunity. If you’re concerned about symptoms or health risks, discuss them with your doctor.
Can I get this test if I’m not showing symptoms?
Yes, your doctor may order this test even if you’re asymptomatic. It’s often used for screening, monitoring, or research purposes, especially in groups at higher risk for EBV-related conditions.
How long will it take to get my results?
Results are typically ready within 2–5 business days, depending on your lab’s processing time. Your healthcare provider will contact you with the results and any next steps.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy