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Epstein-Barr Virus Nuclear Antigen IgG Immunoassay (Serum/Plasma)

Published: August 9, 2026Updated: August 16, 2026

This test measures the presence of Epstein-Barr virus (EBV) antibodies in your blood, specifically IgG antibodies against the nuclear antigen of the virus. These antibodies develop after infection and can persist long-term.

Quick summary

["This test helps diagnose or monitor past EBV infection, which can occur without symptoms."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
26705-4
Short code
EBV NA IgM Titr Ser
Synonyms
EBV NA IgM Titr Ser
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms like fatigue, sore throat, or swollen lymph nodes that could suggest EBV infection. It may also be used to check for chronic infections in people with weakened immune systems or to evaluate symptoms in children or adults who test negative for other infections.

What to Expect Before the Test

No special preparation is needed. You may have a blood sample drawn from a vein in your arm. If you’re on blood-thinning medication, let your provider know before the test.

What the Test Results Mean

Positive results indicate the presence of IgG antibodies, suggesting you’ve had an EBV infection at some point. Negative results mean no detectable antibodies, which could mean you’ve never been infected or the test was taken too early.

Common Reasons for Testing

EBV IgG testing is often used to confirm past infection rather than active illness. It’s less common for diagnosing recent infection because IgG antibodies develop slowly after exposure.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Positive IgG results are typically not urgent for treatment but confirm past exposure. If you’re immunocompromised, these antibodies may indicate a history of infection that could affect immune function. Always discuss results with your provider for personalized interpretation.

Short name

EBV IgG Antibody (Serum/Plasma)

Frequently asked questions

How long does it take to get results from this test?
Results are usually available within 24 to 48 hours, depending on your lab’s processing schedule. Your healthcare provider will contact you with the final results.
Can I have a repeat test if my first result is unclear?
If your initial result is borderline or unclear, your provider may recommend retesting or additional testing (like EBV IgM) to better understand your infection history.
Does this test detect active EBV infection?
No, this test specifically measures IgG antibodies, which develop after an infection and do not indicate active disease. For active infection, IgM antibodies or viral load testing may be needed.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy