Serum or Plasma Protein Electrophoresis by Bromocresol Green (BCG) Method

What This Test Measures

The test separates proteins into major categories—such as albumin, alpha-globulins, beta-globulins, and gamma-globulins—using a dye (bromocresol green) that binds to specific protein groups. This helps identify abnormal protein patterns, which may signal conditions like multiple myeloma, liver disease, or kidney problems.

Why It’s Ordered

Your healthcare provider may recommend this test if you have symptoms like unexplained weight loss, fatigue, swelling, or if lab results show unusual protein levels. It’s also used as part of routine monitoring for certain blood disorders.

Sample Collection and Preparation

A blood sample is drawn from a vein, typically in your arm. The blood is then processed to separate serum or plasma, which is sent to the lab for analysis. No special preparation is needed, but fasting may be advised depending on your specific order.

Common Conditions Monitored

This test helps identify conditions like multiple myeloma (a cancer of plasma cells), chronic liver disease, nephrotic syndrome (kidney disease causing protein loss), or inflammatory disorders. Abnormal patterns may also suggest infections or autoimmune diseases.