Skip to content

Serum or Plasma Substance Concentration (Bromocresol Green Dye Binding)

Published: August 9, 2026Updated: August 16, 2026

This test measures how bromocresol green dye binds to proteins in your blood, often used to assess protein levels or liver function. The method involves mixing the dye with serum or plasma and observing how much binds to proteins.

Quick summary

["This test helps evaluate protein status or liver health by tracking dye-protein interactions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
32844-3
Short code
EBV VCA IgG sp2 Ser-aCnc
Synonyms
EBV VCA IgG sp2 Ser-aCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

The test detects the concentration of a specific dye (bromocresol green) that binds to proteins in your blood. When the dye binds, it changes color, which is measured to estimate protein levels or functional capacity. This is sometimes used in research or specialized clinical settings.

Why It Might Be Ordered

Your healthcare provider may order this test if they suspect conditions affecting protein synthesis, liver function, or other metabolic processes. It can also be part of broader investigations for nutritional deficiencies or certain diseases.

Sample Collection and Preparation

Blood is drawn into a tube that separates serum (liquid part after clotting) or plasma (liquid part before clotting). The sample is then processed to isolate the dye-protein interactions for analysis.

How Results Are Interpreted

Results are typically qualitative (yes/no binding) or semi-quantitative, depending on the method. Higher binding may indicate normal protein levels, while altered binding could suggest liver disease, malnutrition, or other conditions affecting protein function.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

BCG Dye Binding Test

Frequently asked questions

How might this test help diagnose or monitor a condition?
This test is less commonly used in routine clinical practice but may be employed in research, specialized diagnostics, or indirect assessments of protein-related disorders. It can provide insights into protein binding capacity, which may correlate with liver function or nutritional status in certain cases.
What are the typical reference ranges for this test?
Reference ranges are not standardized for this test due to its specialized or research-focused use. Your results will be compared to your own baseline or clinical context rather than a general range.
What should I expect during or after the blood draw?
You may experience mild discomfort at the needle site, but it usually resolves quickly. Avoid strenuous activity for a few hours afterward. If you experience excessive bruising or pain, contact your provider.
  1. 1
  2. 2
  3. 3

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy