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Total Protein with Albumin/Globulin Separation (Serum)

Published: August 9, 2026Updated: August 16, 2026

This test measures your blood’s total protein levels and breaks down the protein components—albumin and globulins—often used to assess liver function, kidney health, or nutritional status.

Quick summary

["Helps check protein balance and identify potential health issues in your blood."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
30137-4
Short code
EBV VCA IgM sp2 Ser Ql
Synonyms
EBV VCA IgM sp2 Ser Ql
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Is Protein in Blood?

Blood proteins, including albumin and globulins, play key roles in transporting nutrients, maintaining fluid balance, and supporting immune function. Albumin, the most abundant protein, helps keep fluids in blood vessels, while globulins include antibodies and other proteins that fight infections.

Why Might This Test Be Ordered?

Your doctor may request this test if you have symptoms like swelling, unexplained weight loss, liver disease, kidney problems, or signs of malnutrition. It can also help monitor chronic conditions like cirrhosis or kidney disease.

How Is This Test Performed?

A blood sample is drawn from a vein, usually in your arm. The serum (liquid part after clotting) is then analyzed to measure total protein and its components using standard laboratory techniques.

What Are Common Results?

Results show total protein concentration and the ratio of albumin to globulins. While specific ranges vary by lab, abnormal results may signal conditions like dehydration, liver disease, or protein-losing disorders.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Total Protein Profile

Frequently asked questions

How long does it take to get my results?
Results are typically available within 1–3 business days, depending on your lab. Your doctor will contact you once they’re ready.
What does a low albumin level mean?
A low albumin level may suggest liver disease, kidney problems, or poor nutrition. Your doctor will review your full medical picture to determine the cause and next steps.
Can diet affect protein test results?
Dietary protein intake may influence albumin levels, but results are usually interpreted in the context of your overall health. Avoid extreme diets or supplements before testing unless advised by your doctor.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy