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C-reactive protein (CRP) in serum/plasma

Published: August 9, 2026Updated: August 16, 2026

This test measures a protein produced by your liver in response to inflammation, often used to check for low-grade inflammation or infection.

Quick summary

["Helps track subtle inflammation that may not show other symptoms."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
47066-6
Short code
EBV VCA IgM Titr Fld IF
Synonyms
EBV VCA IgM Titr Fld IF
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
if
CPT
86430
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why It’s Ordered

Your doctor may order this test if you have symptoms like fatigue, joint pain, or unexplained fevers, or if you’re at risk for conditions like heart disease, autoimmune disorders, or chronic infections. It’s also used to monitor treatment progress for certain conditions.

What to Expect Before the Test

No special preparation is needed. You may have a blood draw from a vein in your arm, or if testing urine, you’ll provide a urine sample. Avoid strenuous activity or heavy meals 24 hours before testing if instructed.

What the Results Mean

Results are interpreted by your healthcare provider based on your overall health and symptoms. Higher levels may indicate inflammation, infection, or other health issues, while lower levels suggest minimal inflammation.

Common Conditions Monitored

This test is often used to monitor conditions like cardiovascular disease, rheumatoid arthritis, lupus, or other inflammatory diseases. It can also help assess response to treatments.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

CRP (High-Sensitivity)

Frequently asked questions

What does a high CRP level mean?
A high CRP level suggests inflammation or infection, but it doesn’t always point to a specific cause. Your doctor will consider other factors, like symptoms, medical history, and test results, to determine the next steps.
Can diet affect CRP levels?
Yes, diet can influence CRP levels. Eating a balanced diet rich in fruits, vegetables, and omega-3 fatty acids may help lower inflammation. Avoiding processed foods, excessive sugar, and unhealthy fats can also support lower CRP levels.
How often should I get this test?
Your doctor will determine the frequency of testing based on your health condition and needs. Regular monitoring may be recommended if you have chronic inflammation or a history of related diseases.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy