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Escherichia coli Antibody (IgG) in Serum or Plasma by Immunoassay

Published: August 9, 2026Updated: August 16, 2026

This test measures your immune system’s response to bacteria called *Escherichia coli* (E. coli) by detecting antibodies (IgG) your body produces to fight them. It helps identify past exposure or immune reaction to these bacteria.

Quick summary

["This test helps assess immune response to common gut bacteria, useful in diagnosing infections or evaluating immune function."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
105765-2
Short code
E coli DNA Ct Bld Pos Qn NAA+probe
Synonyms
E coli DNA Ct Bld Pos Qn NAA+probe
Category
chemistry
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What This Test Measures

The test detects IgG antibodies specific to *E. coli*, a type of bacteria commonly found in the digestive tract. These antibodies indicate your immune system has encountered E. coli before, either through infection or vaccination (e.g., oral vaccines). The presence of these antibodies suggests your body is recognizing and responding to this bacterium.

Why It Might Be Ordered

Your healthcare provider may order this test if you have symptoms of infection (e.g., diarrhea, fever), if you’ve had recent exposure to E. coli, or if you’re being evaluated for immune-related conditions. It can also help monitor immune responses in certain medical situations.

How the Test Works

A small blood sample is taken from your arm. The serum or plasma is then tested using an immunoassay method to detect IgG antibodies against E. coli. This method uses labeled antibodies to identify and quantify your immune response.

What the Results Mean

A positive result means your body has produced IgG antibodies to E. coli, indicating prior exposure. A negative result suggests no detectable antibodies, meaning either you’ve never been exposed or your immune system hasn’t mounted a response yet. Results are qualitative (present or absent) and not tied to specific numeric ranges.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

E. coli antibodies can be useful in diagnosing or confirming past infections, especially in cases where symptoms are unclear or recurrent. They may also help evaluate immune function in patients with chronic gastrointestinal issues or immune disorders. However, this test alone cannot confirm an active infection—it only shows immune memory.

Short name

E. coli Antibody Test

Frequently asked questions

Will this test show if I currently have an E. coli infection?
No, this test measures antibodies produced by your immune system in response to past exposure. It does not detect active infection or current bacterial presence. If you suspect an active infection, your provider may order additional tests.
How long does it take to get results?
Results are typically available within 24 to 48 hours, depending on lab processing times. Your healthcare provider will discuss the results with you during your follow-up visit.
Can I take anything before this test?
No special preparations are needed. However, inform your provider about any medications or supplements you’re taking, as some may affect blood test results.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy