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Escherichia coli DNA in urine (qualitative probe-based method)

Published: August 9, 2026Updated: August 16, 2026

This test detects the presence of genetic material from *Escherichia coli* bacteria in your urine, which may indicate a urinary tract infection (UTI) caused by this specific type of bacteria.

Quick summary

["A UTI probe for E. coli DNA helps confirm infection and guide treatment."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
99019-2
Short code
E coli DNA Ur Ql NAA+probe
Synonyms
E coli DNA Ur Ql NAA+probe
Category
chemistry
Sample
urine
Container
Sterile urine container
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why This Test Matters

Urinary tract infections (UTIs) are common and can cause discomfort, pain, or frequent urination. While many UTIs are caused by bacteria like *E. coli*, some infections may not respond to standard antibiotics. This test helps identify if the infection is caused by *E. coli* DNA, which can help your healthcare provider choose the best treatment.

How the Test Works

This test uses a specialized probe to detect genetic material (DNA) from *E. coli* bacteria in your urine. If the probe finds E. coli DNA, it confirms the presence of this specific bacteria in your urine, which may mean you have a UTI caused by it.

Sample Collection

You’ll need to provide a clean-catch urine sample (midstream urine) or a urine specimen collected in a sterile container. Your healthcare provider will explain the process to ensure the sample is accurate.

What to Expect

The test is typically done as part of a routine urine analysis or if you have symptoms of a UTI. Results are usually available within 24 to 48 hours, depending on your lab’s process.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

E. coli DNA in urine (qual)

Frequently asked questions

What does a positive result mean?
A positive result indicates the presence of *Escherichia coli* DNA in your urine, strongly suggesting a UTI caused by this bacteria. This can help your healthcare provider confirm the diagnosis and tailor treatment, such as antibiotics, to target the infection effectively.
What does a negative result mean?
A negative result means no *E. coli* DNA was detected in your urine sample. However, other bacteria or non-bacterial causes of UTI symptoms could still be present. Your healthcare provider may recommend further testing or different treatments based on your symptoms and lab results.
How often should I get this test?
This test is usually recommended if you have symptoms of a UTI (e.g., frequent urination, pain, or cloudy urine) or if your doctor suspects a UTI caused by *E. coli*. It’s not a routine screening test unless advised by your healthcare provider.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy