Eosinophil count in cerebrospinal fluid (CSF) by quantitative nephelometry
This test measures the number of eosinophils, a type of white blood cell, in your cerebrospinal fluid (CSF). Eosinophils are part of the immune system and can be elevated in certain conditions affecting the brain or spinal cord.
["Elevated eosinophils in CSF may signal inflammation or infection in the central nervous system."]
Key facts at a glance
- LOINC
- 14324-8
- Short code
- E coli K1 Ag CSF Ql LA
- Synonyms
- E coli K1 Ag CSF Ql LA
- Category
- chemistry
- Sample
- csf
- Container
- Sterile tube
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- la
- Specimen volume
- 1-2 mL
- Stability
- Immediate analysis required, Refrigerated: 1h
- Hemolysis max
- 200
- TAT
- 4–24 hours
- Order
- routine
Why Might This Test Be Ordered?
Your healthcare provider may recommend this test if you have symptoms like headaches, neck stiffness, confusion, or neurological issues that could suggest conditions such as meningitis, encephalitis, or certain types of brain inflammation. It may also be used to monitor treatment responses or investigate unexplained neurological symptoms.
What Does the Test Involve?
A small amount of cerebrospinal fluid is collected through a procedure called a lumbar puncture (spinal tap). The fluid is then analyzed in the lab to count eosinophils using a specialized technique called nephelometry.
What Are Common Causes of Elevated Eosinophils in CSF?
Elevated eosinophils in CSF can occur in conditions like eosinophilic meningitis, certain parasitic infections, allergic reactions affecting the central nervous system, or rare inflammatory disorders. However, the exact cause often requires additional testing and clinical correlation.
How Is the Test Performed?
The test involves a simple procedure where a needle is inserted into your lower back to collect CSF. The fluid is then sent to a lab for analysis. The lab uses nephelometry, a method that detects particles in the fluid to count eosinophils accurately.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical Significance: Elevated eosinophils in CSF can indicate specific inflammatory or infectious processes in the central nervous system, such as eosinophilic meningitis or certain parasitic infections. While less common, these findings can guide further diagnostic steps, including additional imaging, cultures, or specialized tests to identify the underlying cause.
Short name
CSF Eosinophil Count
Frequently asked questions
What does a high or low eosinophil count in CSF mean?
How long does it take to get results from this test?
Can I eat or drink before this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy