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Escherichia coli DNA in stool by nucleic acid probe

Published: August 9, 2026Updated: August 16, 2026

This test detects genetic material from *Escherichia coli* (E. coli), a type of bacteria commonly found in the intestines. It helps identify if harmful strains are present in your stool.

Quick summary

["Looks for E. coli DNA to check for possible infection risk in stool samples."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
99089-5
Short code
E coli K1 DNA CSF Ql NAA+probe
Synonyms
E coli K1 DNA CSF Ql NAA+probe
Category
chemistry
Sample
csf
Container
Sterile tube
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
Specimen volume
1-2 mL
Stability
Immediate analysis required, Refrigerated: 1h
Hemolysis max
200
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may order this test if you have symptoms like diarrhea, abdominal pain, or fever that could suggest a bacterial infection. It’s also used to screen for certain gastrointestinal conditions or after exposure to contaminated food/water.

How the Test Works

A small sample of your stool is tested for E. coli DNA using a specialized probe that binds to its genetic material. This method is highly sensitive and can detect even small amounts of bacteria, though it doesn’t distinguish between harmful and harmless strains.

Sample Collection

You’ll provide a fresh stool sample (usually collected in a sterile container) during a visit to your healthcare provider’s office or clinic. The sample is then sent to a lab for processing.

What to Expect After the Test

Results are typically ready within 1–3 business days. If the test is positive, your provider may recommend further testing (like culture) to identify the specific E. coli strain or guide treatment.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

E. coli DNA stool test

Frequently asked questions

Is E. coli DNA always harmful?
No. While E. coli DNA in stool can indicate a possible infection, not all strains are dangerous. Some harmless strains naturally live in the intestines. A positive result triggers further evaluation to assess risk and guide next steps.
Can this test replace a stool culture?
Not entirely. While this test detects DNA, it doesn’t confirm live bacteria or identify antibiotic resistance. A culture may be needed for more detailed results.
What if I have recurring diarrhea?
If you experience persistent symptoms, discuss the test results with your provider. They may recommend additional tests (e.g., stool culture, bloodwork) to pinpoint the cause and tailor treatment.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy