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Serum Creatinine Concentration (Mass Concentration)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of creatinine, a waste product from muscle metabolism, in your blood serum. It helps assess kidney function.

Quick summary

["A creatinine test helps doctors check how well your kidneys are filtering waste from your blood."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
20817-3
Short code
E coli K88 TSMI Ql IF
Synonyms
E coli K88 TSMI Ql IF
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
if
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Matters

Creatinine is a byproduct of muscle breakdown and is filtered out of your blood by your kidneys. High levels can indicate reduced kidney function, while low levels may suggest overhydration or other conditions. This test is often used alongside other measures to monitor kidney health, especially in people with diabetes, hypertension, or a history of kidney disease.

What to Expect Before the Test

You can eat and drink normally before this test. No special preparation is needed unless your doctor instructs otherwise. Bring any medications you’re currently taking, as some may affect results.

How the Test Works

A blood sample is taken from a vein, usually in your arm. The sample is sent to a lab where it’s analyzed to measure creatinine levels using a specialized method, often automated and highly precise.

Possible Results and Interpretation

Results are typically reported in units of milligrams per deciliter (mg/dL) or milligrams per liter (mg/L). While reference ranges vary by lab, higher than expected levels may signal kidney issues, while very low levels might warrant further investigation into hydration status or other health factors.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Creatinine Level

Frequently asked questions

How often should I get this test?
Your doctor will determine how often you need this test based on your health history, symptoms, and overall condition. For example, people with diabetes or kidney disease may need it more frequently than others.
Can diet affect my creatinine levels?
Dietary protein intake can influence creatinine levels, as muscle breakdown produces creatinine. However, short-term changes in diet are unlikely to cause significant fluctuations. Always follow your doctor’s advice regarding dietary adjustments.
What if my results are out of the normal range?
If your results are abnormal, your doctor will discuss them with you and may recommend further testing or adjustments to your treatment plan. This could include monitoring kidney function more closely or exploring other potential causes.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy