Escherichia coli (E. coli) bacterial culture and antibiotic susceptibility screening (serum/plasma)
This test checks for the presence of *Escherichia coli* bacteria in your blood, which can indicate serious infections like sepsis. It also helps determine if antibiotics are effective against these bacteria.
["A positive result may signal a blood infection requiring urgent medical attention and tailored antibiotic treatment."]
Key facts at a glance
- LOINC
- 44087-5
- Short code
- E coli O157 Ag Spec Ql
- Synonyms
- E coli O157 Ag Spec Ql
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What This Test Measures
The test involves culturing blood samples to identify *E. coli* bacteria. If bacteria are found, further testing (like antibiotic susceptibility) helps guide treatment choices. This is typically done using a blood culture method, which may take several days to complete.
Why It’s Done
Doctors order this test if you have symptoms like fever, chills, rapid heartbeat, or confusion—common signs of a blood infection. It’s also used when you’re at higher risk, such as after surgery, chemotherapy, or if you have weakened immune systems.
Sample Collection and Process
A blood sample is drawn from a vein, usually in your arm. The sample is then sent to a lab where it’s cultured in special growth media to detect *E. coli* and other bacteria. If bacteria are present, they’ll grow into colonies that can be identified under a microscope or tested further.
Antibiotic Sensitivity Testing
If *E. coli* is confirmed, additional testing may be done to see which antibiotics work best against it. This involves exposing the bacteria to different antibiotics and measuring how they grow or survive. This helps prevent antibiotic resistance.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical Significance
Short name
E. coli in Blood
Frequently asked questions
Early detection of *E. coli* in the blood is critical because untreated infections can lead to severe complications, including organ failure or death. This test helps doctors diagnose sepsis quickly and start appropriate treatment, such as intravenous antibiotics.
How long will I need to wait for results?
What are the risks or side effects of this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy