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E. coli O157:H7 Antibody Screening Test (Serum/Plasma)

Published: August 9, 2026Updated: August 17, 2026

This test detects antibodies in your blood that may indicate past exposure to *Escherichia coli* (E. coli) strain O157:H7, a bacterium often linked to foodborne illnesses.

Quick summary

["Helps identify possible infection history without testing for the bacteria itself."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
82204-9
Short code
E coli O157 DNA Stl Ql NAA+n-prb
Synonyms
E coli O157 DNA Stl Ql NAA+n-prb
Category
chemistry
Sample
stool
Container
Clean container
Units
N/A
Ref low
10
Ref high
40
Critical range
— – 500 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
non-probe-amp-tar
CPT
84484
SNOMED
302774002
Specimen volume
5 g
Stability
Refrigerated: 24h, Frozen: 7d
TAT
4–24 hours
Order
routine

What This Test Measures

The test looks for antibodies produced by your immune system in response to exposure to *E. coli* O157:H7. Antibodies are proteins your body makes to fight infections. This screening is not a direct test for the bacteria but can help track immune response if you’ve been exposed.

Why It Might Be Ordered

Your healthcare provider may order this test if you’ve had symptoms like severe stomach cramps, bloody diarrhea, or if you’ve been exposed to contaminated food/water. It’s also used in outbreaks or research settings to monitor immune response.

Sample Collection and Preparation

A blood sample is drawn from your arm, and the serum or plasma is tested for antibodies. No special preparation is needed, but fasting may be advised depending on your provider’s instructions.

What to Expect After the Test

Results are typically ready within 1–3 business days. You’ll discuss them with your provider, who may recommend further testing (e.g., stool culture) if symptoms persist or exposure is suspected.

Reference range

Adult: 10-40 U/LN/A

Specimen: stool

No special preparation required. Avoid fatty meals before the test if possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Positive results suggest your immune system has encountered *E. coli* O157:H7, but they don’t confirm active infection. This test is often used alongside other diagnostic tools (like stool cultures) to guide treatment or outbreak investigations. False positives can occur with prior exposure or cross-reactions, so results should be interpreted by a healthcare provider.

Short name

E. coli O157:H7 Antibody Screen

Frequently asked questions

Could this test show if I currently have an E. coli infection?
No. This test detects antibodies produced after exposure, not the bacteria itself. If you suspect an active infection, your provider may order a stool culture or other tests.
Why would my doctor order this test if I don’t have symptoms?
Possible reasons include investigating foodborne illness outbreaks, monitoring immune response after exposure, or evaluating risk in high-exposure settings (e.g., farms, hospitals). Your provider will discuss the reason with you.
What does a positive result mean for my health?
A positive result indicates your body has likely encountered *E. coli* O157:H7 before, but it doesn’t guarantee you’re currently infected. Follow-up testing or advice from your provider is needed to assess your situation.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy