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Escherichia coli (E. coli) DNA in Urine (Qualitative Probe-Based Test)

Published: August 9, 2026Updated: August 16, 2026

This test detects the presence of genetic material from *Escherichia coli* bacteria in your urine, which may help identify urinary tract infections (UTIs) caused by these bacteria.

Quick summary

["A simple urine test to check for possible UTI caused by E. coli bacteria."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
103555-9
Short code
E coli O157H7 DNA Wnd Ql NAA+probe
Synonyms
E coli O157H7 DNA Wnd Ql NAA+probe
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may order this test if you have symptoms like frequent urination, pain or burning during urination, cloudy or strong-smelling urine, or fever—common signs of a UTI. It helps confirm if the infection is caused by *E. coli* or other bacteria.

How the Test Works

A small urine sample is collected and analyzed using a specialized probe to detect *E. coli* DNA. This method is highly sensitive and can detect even small amounts of bacterial genetic material.

What to Expect Before the Test

No special preparation is needed. You may urinate into a clean container at home or collect a sample in a sterile cup during a doctor’s visit. Avoid using personal hygiene products (like feminine sprays) before testing.

What to Expect During the Test

The test involves a quick urine sample. Results are typically available within hours or days, depending on lab processing. Your provider will discuss the findings with you.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Positive results strongly suggest a UTI caused by *E. coli*, which is the most common bacterial cause of UTIs. Negative results mean no detectable *E. coli* DNA, but other causes of UTI symptoms (like yeast infections or non-bacterial irritation) may still be present. This test helps guide treatment decisions, such as antibiotics for bacterial infections.

Short name

E. coli DNA in Urine (Qualitative)

Frequently asked questions

What does a positive result mean?
A positive result indicates the presence of *E. coli* DNA in your urine, strongly suggesting a urinary tract infection (UTI) caused by these bacteria. Your provider will likely recommend further testing or treatment, such as antibiotics.
What does a negative result mean?
A negative result means no *E. coli* DNA was detected in your urine sample. While this doesn’t rule out other causes of UTI symptoms (like yeast infections or non-bacterial irritation), it suggests the infection may not be caused by *E. coli*. Follow-up testing may be needed if symptoms persist.
Can I take antibiotics before this test?
No, it’s best to avoid antibiotics before this test, as they can reduce the presence of *E. coli* DNA and affect the accuracy of results. If you’ve recently taken antibiotics, inform your provider before the test.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy