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C-reactive protein (CRP) in plasma by chemiluminescent immunoassay (clia)

Published: August 9, 2026Updated: August 16, 2026

This test measures the level of C-reactive protein in your blood plasma, a marker often checked for signs of inflammation or infection.

Quick summary

["CRP helps track inflammation, guiding decisions about treatment or further testing."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
63428-7
Short code
EC stx2 Spec QI NAA+probe
Synonyms
EC stx2 Spec QI NAA+probe
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order this test to monitor conditions like infections, autoimmune diseases, or inflammation. It can also help assess risk for heart disease or evaluate response to treatment for conditions such as arthritis or other inflammatory disorders.

What Does a High or Low Result Mean?

Elevated CRP levels often indicate inflammation or infection, but results alone don’t diagnose a specific condition. A provider will interpret results in the context of your symptoms, medical history, and other tests.

Sample Preparation

This test uses plasma, a component of whole blood separated during processing. You’ll typically provide a blood draw, and your sample will be processed to isolate plasma for testing.

Common Conditions Monitored

CRP is commonly checked in people with suspected infections, chronic inflammatory diseases (e.g., rheumatoid arthritis), or those at higher risk for cardiovascular issues. It may also be used to monitor treatment progress in certain conditions.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

CRP (Plasma)

Frequently asked questions

What does a CRP test measure?
A CRP test measures the concentration of C-reactive protein in your blood plasma, which rises when your body is responding to inflammation or infection.
How often should I get a CRP test?
Frequency depends on your medical needs. Your healthcare provider will determine how often to check based on your symptoms, diagnosis, or ongoing treatment plan.
Can lifestyle changes affect CRP levels?
Yes, lifestyle factors like diet, exercise, smoking, and stress can influence CRP levels. Reducing inflammation through healthy habits may lower CRP, but results vary by individual.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy