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Neutrophil count (absolute, serum/plasma)

Published: August 9, 2026Updated: August 17, 2026

This test measures the number of neutrophils, a type of white blood cell, in your blood. Neutrophils help fight infections and inflammation.

Quick summary

["Neutrophils are key defenders against bacterial infections; low or high levels may signal health concerns."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
100976-0
Short code
EDN SerPl-mCnc
Synonyms
EDN SerPl-mCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
0
Ref high
17
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Neutrophils Do in Your Body

Neutrophils are a critical part of your immune system. They rush to infection sites to destroy bacteria and other harmful invaders. When your body detects an infection, neutrophil levels often rise to help clear the threat. This test helps doctors assess whether your immune response is functioning properly or if there may be an underlying issue.

When This Test Might Be Ordered

Your doctor may recommend this test if you have symptoms like frequent infections, unexplained fevers, or signs of inflammation. It’s also used to monitor conditions like leukemia, autoimmune diseases, or after treatments that affect the immune system.

What to Expect Before the Test

No special preparation is needed for this blood test. You’ll have a small needle inserted into your arm or hand to draw a blood sample. The process usually takes a few minutes, and you may feel a brief pinch. If you’re on blood thinners, let your doctor know before the test.

What the Results Mean

Results are reported as the number of neutrophils per microliter (µL) of blood. Very low levels may indicate immune deficiencies or bone marrow disorders, while very high levels could suggest infections, inflammation, or other conditions. Your doctor will interpret the results in the context of your overall health and symptoms.

Reference range

NCBI: NSE 0-17 ng/mLN/A

Specimen: serum

No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Absolute Neutrophil Count (ANC)

Frequently asked questions

Why might my doctor be concerned about my neutrophil count?
Low neutrophil counts can make you more susceptible to infections, especially bacterial ones. High counts may signal active infections, inflammation, or conditions like chronic granulomatous disease. Your doctor will use these results alongside other tests and symptoms to guide treatment.
What if my neutrophil count is outside the normal range?
If your results are abnormal, your doctor may recommend further testing, such as blood cultures, imaging, or additional immune function tests. They may also adjust medications or treatments to address the underlying cause.
Can diet or lifestyle affect neutrophil counts?
Diet and lifestyle factors like stress, poor sleep, or certain medications can influence white blood cell counts. Avoiding excessive alcohol, staying hydrated, and maintaining a balanced diet may support overall immune health, but this test alone won’t show direct dietary effects.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy