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Electrophoresis of Serum Proteins (Qualitative)

Published: August 9, 2026Updated: August 16, 2026

This test measures the different types of proteins in your blood using a technique called electrophoresis. It helps identify abnormalities in protein distribution that may indicate conditions like kidney disease, liver problems, or certain cancers.

Quick summary

["Electrophoresis helps doctors spot unusual protein patterns that could signal health concerns."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
93200-4
Short code
EDS Multigene Anl Bld/T
Synonyms
EDS Multigene Anl Bld/T
Category
chemistry
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
molgen
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What This Test Measures

Electrophoresis separates blood proteins into distinct bands based on their size and electrical charge. The test typically looks at five main protein zones: albumin, alpha-1 globulins, alpha-2 globulins, beta globulins, and gamma globulins (antibodies). Abnormal patterns may appear if protein production or breakdown is disrupted.

Common Conditions Detected

This test can reveal conditions such as multiple myeloma (a cancer of plasma cells), chronic liver disease, kidney disease, or certain autoimmune disorders. High or low levels of specific proteins may also suggest nutritional deficiencies or metabolic disorders.

Sample Collection and Preparation

A blood sample is drawn from your arm, and the serum (liquid part after clotting) is sent to the lab. No special preparation is needed, but fasting may be advised depending on your doctor’s instructions.

How Results Are Interpreted

Results are compared to standard patterns. An abnormal pattern may require further testing, such as additional protein analysis or imaging, to determine the underlying cause.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Serum protein electrophoresis is a key diagnostic tool for identifying protein abnormalities that can guide treatment decisions. For example, elevated gamma globulins may suggest immune disorders, while abnormal albumin levels could indicate liver or kidney disease. Early detection helps manage conditions more effectively.

Short name

Serum Protein Electrophoresis (Q)

Frequently asked questions

Why might my doctor order this test?
Your doctor may recommend this test if you have symptoms like unexplained weight loss, fatigue, swelling, or if they suspect conditions like multiple myeloma, liver disease, or kidney problems.
What does it mean if my results show unusual protein bands?
Unusual bands could indicate a health issue like cancer, infection, or metabolic disorder. Your doctor will discuss the findings with you and may suggest additional tests to clarify the cause.
Do I need to prepare for this test?
No special preparation is usually needed, but follow your doctor’s instructions regarding fasting or timing of the test.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy