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Eastern Equine Encephalitis Virus IgG and IgM Antibodies, Serum — Immunoassay

Published: August 9, 2026Updated: August 16, 2026

A serum immunoassay detects IgG and IgM antibodies to eastern equine encephalitis virus, helping evaluate previous exposure or a possible recent infection.

Quick summary

["Detectable antibodies may indicate previous exposure or a recent eastern equine encephalitis virus infection, but results must be interpreted with symptoms, timing, and other testing."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
24006-9
Short code
EEEV IgG+IgM Ser-Imp
Synonyms
EEEV IgG+IgM Ser-Imp
Category
liver
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What is this test?

This blood test looks for IgG and IgM antibodies against eastern equine encephalitis virus, a mosquito-borne virus that can cause inflammation of the brain. It detects the body's immune response rather than the virus itself.

Why might I need this test?

Your clinician may order this test if you have fever, headache, confusion, seizures, or other neurologic symptoms after potential mosquito exposure. It may also be used when infection with this virus is suspected despite a low initial suspicion.

How is the test performed?

A blood sample is collected, and the serum is analyzed using an immunoassay to detect virus-specific IgG and IgM antibodies. Because early antibody testing may be negative, repeat testing on a later sample may be needed.

How do I prepare for the test?

Fasting is usually not required for this serum test unless your clinician gives different instructions. Tell your clinician about recent travel, mosquito exposure, prior infections, vaccination history, and when your symptoms began.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

IgG antibodies generally suggest exposure to eastern equine encephalitis virus at some time, while IgM antibodies may support a recent infection. However, IgM can remain detectable for an extended period or occur with other infections, so a positive result alone does not establish active disease. Results are interpreted alongside symptom timing, possible exposure, repeat antibody testing, and other laboratory findings.

Short name

Eastern equine encephalitis virus antibodies

Frequently asked questions

What does a positive IgG result mean?
It usually indicates that your immune system has encountered eastern equine encephalitis virus, either through a past infection or a less common cross-reaction. It does not by itself prove that you currently have the disease.
What does a positive IgM result mean?
IgM may suggest a recent infection, particularly when symptoms began recently. Because it can persist or sometimes be falsely positive, your clinician will interpret it with your symptoms, exposure history, and other test results.
Can this test rule out eastern equine encephalitis virus infection?
No. Antibodies may not be detectable early in an infection, so a negative result does not always exclude the virus. Repeat testing and additional clinical or laboratory evaluation may be necessary.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy