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Eastern Equine Encephalitis Virus IgM Antibodies, Serum

Published: August 9, 2026Updated: August 16, 2026

Detects IgM antibodies to the Eastern equine encephalitis virus in serum, helping evaluate a possible recent infection.

Quick summary

["A positive result may support a recent EEE virus infection, but it may require confirmation with additional testing."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
110961-0
Short code
EEEV IgM Msmt Ser
Synonyms
EEEV IgM Msmt Ser
Category
liver
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What is this test?

This blood test looks for IgM antibodies against the Eastern equine encephalitis (EEE) virus. IgM antibodies are the immune response most often associated with a recent infection.

Why might I need this test?

The test may be ordered when someone has fever, severe headache, confusion, seizures, or other possible signs of a mosquito-borne infection after spending time in an area where EEE virus occurs.

How is the test performed?

A blood sample is drawn, and the serum is separated from the cells and tested for EEE virus-specific IgM antibodies using a laboratory method.

How do I prepare for the test?

Fasting is generally not required, but follow the laboratory's instructions. Tell your clinician about recent mosquito exposure, travel or outdoor activity in affected areas, symptoms, and when they began.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

EEE virus IgM antibody

Frequently asked questions

What does a positive EEE virus IgM result mean?
It may indicate a recent EEE virus infection, but cross-reactivity with other viruses and the timing of illness must also be considered. Your clinician will interpret the result with your symptoms and exposure history.
Can I have EEE without mosquito exposure?
EEE virus is usually transmitted by infected mosquitoes, so the test is most relevant after exposure in an affected area. Rarely, other routes of transmission have been reported.
Does a negative result rule out EEE?
No. The test may be negative early in the infection before antibodies develop, so a high suspicion of EEE may require additional testing and urgent medical evaluation.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy