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Fecal Calprotectin (Mass Concentration) via Stool Probe

Published: August 9, 2026Updated: August 16, 2026

This test measures a protein found in white blood cells that can indicate inflammation in your digestive tract.

Quick summary

["Helps assess gut inflammation, often used to check for conditions like inflammatory bowel disease (IBD)."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
76584-2
Short code
E faecal cpn60 Swab Ql NAA+probe
Synonyms
E faecal cpn60 Swab Ql NAA+probe
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Matters

Calprotectin is released when white blood cells respond to inflammation in the intestines. High levels may signal chronic inflammation, which can be linked to conditions like Crohn’s disease or ulcerative colitis. This test helps doctors monitor disease activity and guide treatment decisions without relying on invasive procedures like endoscopy.

What to Expect Before the Test

No special preparation is needed. You’ll provide a small stool sample collected using a provided collection kit. The sample is then tested in the lab to measure calprotectin levels. Results are typically available within a few days.

How the Test Works

A stool sample is analyzed using a specialized probe that detects calprotectin, a protein associated with inflammation. The test quantifies the protein’s concentration to determine if inflammation is present or active in your digestive system.

Possible Results and Next Steps

Elevated calprotectin levels may suggest inflammation, while normal levels generally indicate no significant inflammation. Your doctor will interpret results in the context of your medical history and symptoms to determine the next steps, which could include further testing or treatment adjustments.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Fecal Calprotectin

Frequently asked questions

What does elevated calprotectin mean?
Elevated calprotectin levels often point to inflammation in the gastrointestinal tract, such as inflammatory bowel disease (IBD), but they can also be seen in other conditions like infections or certain types of tumors. Your doctor will use these results alongside other tests and symptoms to guide diagnosis and treatment.
How often should I get this test?
The frequency of this test depends on your medical condition and treatment plan. If you have a known gastrointestinal condition like IBD, your doctor may recommend regular monitoring to track inflammation levels. If you’re asymptomatic, this test may not be routinely recommended unless symptoms arise or your doctor suspects inflammation.
Can diet affect my test results?
Dietary changes that significantly alter bowel function, such as extreme fiber intake or certain medications (e.g., antibiotics), may temporarily influence stool consistency or inflammation markers. However, calprotectin levels are generally stable enough that diet changes are unlikely to affect the test results significantly unless they cause noticeable changes in bowel habits or symptoms.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy