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Fecal Immunochemical Test for Occult Blood (FIT) – DNA-Based Probe

Published: August 9, 2026Updated: August 16, 2026

This test detects hidden blood in your stool using a specialized DNA-based probe to help identify potential gastrointestinal bleeding.

Quick summary

["A simple stool test to check for hidden blood, often used to screen for colorectal issues."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
92783-0
Short code
E faecalis DNA Bld Pos Ql NAA+probe
Synonyms
E faecalis DNA Bld Pos Ql NAA+probe
Category
chemistry
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why This Test Matters

Hidden blood in stool (occult blood) can sometimes signal conditions like colorectal cancer, hemorrhoids, or other gastrointestinal problems. This test helps doctors identify if further evaluation is needed without requiring a traditional stool sample collection.

How the Test Works

The test uses a DNA-based probe to detect specific markers in your stool. Unlike traditional chemical tests, this method is more sensitive and specific, helping to catch blood at very low levels that might otherwise go undetected.

What to Expect Before the Test

No special preparation is required. You’ll provide a small sample of stool during your visit, and the test will be processed immediately. Avoid using over-the-counter stool tests or certain medications (like NSAIDs) that may affect results.

What the Results Mean

A positive result means blood is likely present, prompting further testing (like a colonoscopy) to determine the cause. A negative result doesn’t rule out bleeding entirely but suggests no obvious signs of hidden blood in this sample.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

FIT-DNA Probe Test

Frequently asked questions

This test is commonly used as a screening tool for colorectal cancer, especially in individuals at higher risk or as part of routine health checks. Early detection can improve treatment outcomes, so results should always be discussed with your healthcare provider.
A positive result may require additional testing, such as a colonoscopy, to find the source of bleeding or cancer. If you have symptoms like unexplained weight loss, blood in stool, or abdominal pain, this test may be recommended to investigate further.
How often should I get this test? Your doctor will determine the best schedule based on your medical history and risk factors.
This test is usually painless and quick. If you have a history of hemorrhoids or bowel issues, let your doctor know so they can guide you on sample collection to avoid contamination.
Will insurance cover this test? Coverage depends on your plan and whether your doctor orders it for screening or diagnostic purposes.
This test is not the same as a traditional fecal occult blood test (FOBT). The DNA-based probe method is more sensitive and may detect blood at earlier stages than older chemical tests.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy