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Fecal DNA (Nucleic Acid) Probe Test for Pathogen Detection

Published: August 9, 2026Updated: August 16, 2026

This test checks for specific DNA fragments in your stool sample that may indicate the presence of certain bacteria or viruses. It helps identify infections that might not be detected by traditional stool cultures.

Quick summary

["This test can help diagnose infections that may not show up on standard tests, such as certain gastrointestinal pathogens."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
92782-2
Short code
E faecium DNA Bld Pos Ql NAA+probe
Synonyms
E faecium DNA Bld Pos Ql NAA+probe
Category
chemistry
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What This Test Measures

The test uses a specialized probe to detect DNA from specific microorganisms in your stool. These probes are designed to match sequences unique to certain bacteria or viruses, allowing for early detection of infections.

How the Test Works

Instead of growing bacteria in a lab, this test looks for DNA evidence of pathogens. If the pathogen is present, its DNA will bind to the probe, triggering a detectable signal.

Why It Might Be Ordered

Your healthcare provider may order this test if you have symptoms like persistent diarrhea, abdominal pain, or fever that suggest an infection, especially if traditional stool cultures are inconclusive.

Common Uses and Symptoms

This test is often used to investigate gastrointestinal infections caused by bacteria like *Campylobacter*, *Salmonella*, or *Shigella*, as well as viruses such as norovirus or rotavirus. Symptoms may include diarrhea, nausea, vomiting, or blood in stool.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Stool DNA Screening

Frequently asked questions

How soon will I get my results?
Results are typically available within 24 to 48 hours, depending on lab processing times. Follow-up with your healthcare provider to discuss the findings and next steps.
What does a positive result mean?
A positive result indicates the presence of DNA from specific pathogens in your stool. This does not confirm an active infection but suggests a possible presence of the microorganism. Further testing or clinical correlation may be needed to determine the cause of your symptoms.
Can I eat or drink before the test?
Yes, you can eat and drink normally before providing the stool sample. Avoid using laxatives or enemas unless instructed by your healthcare provider, as they may affect the test results.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy