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Estimated Glomerular Filtration Rate (eGFR), Creatinine-Based Calculation — Whole Blood

Published: August 9, 2026Updated: August 17, 2026

A blood-based calculation that estimates how well the kidneys filter waste, usually using the creatinine level and selected personal factors.

Quick summary

["Your eGFR is an estimate of kidney filtering function that helps identify and monitor kidney disease."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
55766-0
Short code
EGFR c.2573T>G Bld/T Ql
Synonyms
EGFR c.2573T>G Bld/T Ql
Category
kidney
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Ref low
90
Ref high
120
Critical range
15 N/A – —
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
molgen
CPT
82565
SNOMED
247997009
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What is this test?

Estimated glomerular filtration rate, or eGFR, is a calculated measure of how well your kidneys remove waste from the blood. It is usually based on a blood creatinine measurement along with information such as age and sex.

Why might I need this test?

Clinicians use eGFR to evaluate and monitor kidney function, including chronic kidney disease, high blood pressure, diabetes, and other conditions that may affect the kidneys. It may also be used to help guide medication dosing and other care.

How is the test performed?

A blood sample is collected, and the laboratory measures creatinine or uses a previously reported creatinine result. The laboratory then calculates eGFR with a standard formula. The calculation is not a direct measurement of filtration.

How do I prepare for the test?

Fasting is generally not required unless your clinician gives specific instructions. Recent illness, dehydration, pregnancy, unusually high muscle mass, and certain medications can affect the result, so tell your clinician about anything that may be relevant.

Reference range

Normal: >90 mL/min/1.73m²N/A

Specimen: whole-blood

No special preparation required. Stay well hydrated.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

A lower eGFR may indicate reduced kidney filtration and can be seen with chronic kidney disease, dehydration, or some acute kidney problems. A higher value may occur with pregnancy or unusually high muscle mass. The result should be interpreted with other kidney tests, symptoms, and your medical history because eGFR is an estimate rather than a direct measurement.

Short name

eGFR

Frequently asked questions

Is eGFR the same as a creatinine test?
No. Creatinine is a substance measured in the blood, while eGFR is calculated from the creatinine level and other factors. The two results are related but provide different information.
Does a low eGFR always mean I have kidney failure?
No. A low eGFR can indicate reduced kidney function, but it does not by itself establish kidney failure. Your clinician will consider the trend over time and other findings.
Can I improve my eGFR?
Kidney function may improve when the cause of reduced function is treated or corrected, such as improving blood sugar or blood pressure control. Some kidney damage may be permanent, so follow your clinician's recommended treatment and monitoring plan.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy